Projects per year
Abstract
In this essay, we reflect how the findings of the preceding papers enabled us to thicken the history of genomics beyond extending the dimension of time. We expanded the number of dimensions across which our historical work operated and signaled how the history of genomics became synchronically intertwined with a range of communities, target species, and research agendas – among them yeast biochemistry, pig and human immunology, systematics, medical genetics, and agricultural genetics. We made sense of these intertwinements with analytic categories to characterize modes of organizing and conducting sequencing, and the relationship between the practices of sequencing and the objectives of those collaborating around it: horizontal and vertical, proximal and distal, directed and undirected, as well as intensive and extensive sequencing.
Our categories emerged as we analyzed and qualitatively interpreted datasets and co-authorship networks. The increasing availability of data and data-analysis tools for historical work provides a new angle on debates concerning the relationship of case studies to bigger pictures in the history of science.
Throughout this special issue, we have characterized genomics as a set of tools that open up connections between actors, institutions, experimental organisms, and historically contingent forms of research. We contend that presenting genomics in this way emphasizes the agency of the communities that mobilized the sequence data and offers a fresh perspective to address the medical and agricultural translation of that data.
We close by proposing ways of extending our approach to new forms of data and connecting these through an ontology.
Our categories emerged as we analyzed and qualitatively interpreted datasets and co-authorship networks. The increasing availability of data and data-analysis tools for historical work provides a new angle on debates concerning the relationship of case studies to bigger pictures in the history of science.
Throughout this special issue, we have characterized genomics as a set of tools that open up connections between actors, institutions, experimental organisms, and historically contingent forms of research. We contend that presenting genomics in this way emphasizes the agency of the communities that mobilized the sequence data and offers a fresh perspective to address the medical and agricultural translation of that data.
We close by proposing ways of extending our approach to new forms of data and connecting these through an ontology.
Original language | English |
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Pages (from-to) | 443-475 |
Number of pages | 33 |
Journal | Historical Studies in the Natural Sciences |
Volume | 52 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1 Jun 2022 |
Keywords / Materials (for Non-textual outputs)
- genomics
- sequencing
- mixed-methods
- social network analysis
- collaboration
- longue-durée history
- quantitative methods
- qualitative methods
Fingerprint
Dive into the research topics of 'Across and within networks: Thickening the history of genomics'. Together they form a unique fingerprint.Projects
- 1 Finished
Research output
- 4 Article
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The bricolage of pig genomics
Lowe, J., Leng, R., Viry, G., Wong, M., Vermeulen, N. & Garcia-Sancho, M., 1 Jun 2022, In: Historical Studies in the Natural Sciences. 52, 3, p. 401-442 42 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The Human Genome Project as a singular episode in the history of genomics
Garcia-Sancho, M., Leng, R., Viry, G., Wong, M., Vermeulen, N. & Lowe, J., 1 Jun 2022, In: Historical Studies in the Natural Sciences. 52, 3, p. 320-360 41 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The sequences and the sequencers: What can a mixed-methods approach reveal about the history of genomics?
Leng, R., Viry, G., Garcia-Sancho, M., Lowe, J., Wong, M. & Vermeulen, N., 1 Jun 2022, In: Historical Studies in the Natural Sciences. 52, 3, p. 277-319 43 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Datasets
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Human, yeast and pig genomics: sequence submissions and first sequence descriptions in the literature (1980-2015)
Wong, M. (Creator), Leng, R. (Creator), Viry, G. (Creator), Liscovsky barrera, R. (Creator) & Garcia Sancho Sanchez, M. (Creator), Edinburgh DataShare, 5 Dec 2019
DOI: 10.7488/ds/2718, https://f1000research.com/articles/8-1200
Dataset