Abstract
Recently we identified a bacterial factor (BimA) required for actin-based motility of Burkholderia pseudomallei. Here we report that Burkholderia mallei and Burkholderia thailandensis are capable of actin-based motility in J774.2 cells and that BimA homologs of these bacteria can restore the actin-based motility defect of a B. pseudomallei bimA mutant. While the BimA homologs differ in their amino-terminal sequence, they interact directly with actin in vitro and vary in their ability to bind Arp3.
Original language | English |
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Pages (from-to) | 7857-7862 |
Number of pages | 6 |
Journal | Journal of Bacteriology |
Volume | 187 |
Issue number | 22 |
DOIs | |
Publication status | Published - Nov 2005 |