Abstract / Description of output
Growth and morphogenesis of filamentous fungi is underpinned by dynamic reorganization and polarization of the actin cytoskeleton. Actin has crucial roles in exocytosis, endocytosis, organelle movement and cytokinesis in fungi, and these processes are coupled to the production of distinct higher-order structures (actin patches, cables and rings) that generate forces or serve as tracks for intracellular transport. New approaches for imaging actin in living cells are revealing important similarities and differences in actin architecture and organization within the fungal kingdom, and have yielded key insights into cell polarity, tip growth and long-distance intracellular transport. In this Review, we discuss the contribution that recent live-cell imaging and mutational studies have made to our understanding of the dynamics and regulation of actin in filamentous fungi.
Original language | English |
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Pages (from-to) | 876-887 |
Journal | Nature Reviews Microbiology |
Volume | 9 |
Early online date | 2 Nov 2011 |
DOIs | |
Publication status | Published - 31 Dec 2011 |
Keywords / Materials (for Non-textual outputs)
- Actin
- Cellular microbiology
- Fungal biology
- Fungi