Action and learning shape the activity of neuronal circuits in the visual cortex

Janelle Mp Pakan, Valerio Francioni, Nathalie L Rochefort

Research output: Contribution to journalReview articlepeer-review

Abstract

Nonsensory variables strongly influence neuronal activity in the adult mouse primary visual cortex. Neuronal responses to visual stimuli are modulated by behavioural state, such as arousal and motor activity, and are shaped by experience. This dynamic process leads to neural representations in the visual cortex that reflect stimulus familiarity, expectations of reward and object location, and mismatch between self-motion and visual-flow. The recent development of genetic tools and recording techniques in awake behaving mice has enabled the investigation of the circuit mechanisms underlying state-dependent and experience-dependent neuronal representations in primary visual cortex. These neuronal circuits involve neuromodulatory, top-down cortico-cortical and thalamocortical pathways. The functions of nonsensory signals at this early stage of visual information processing are now beginning to be unravelled.

Original languageEnglish
Pages (from-to)88-97
Number of pages10
JournalCurrent Opinion in Neurobiology
Volume52
Early online date1 May 2018
DOIs
Publication statusE-pub ahead of print - 1 May 2018

Keywords

  • Journal Article
  • Review

Fingerprint

Dive into the research topics of 'Action and learning shape the activity of neuronal circuits in the visual cortex'. Together they form a unique fingerprint.

Cite this