Addressing kinetic applications in High Content Screening

Edward Ainscow, Neil Carragher

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Traditional drug discovery screening assays tend to employ simplistic endpoint assays that often monitor the activity of a single target. While these approaches are amenable to high-throughput screening they provide limited information on how candidate drugs influence complex biological systems that exist in vivo. Such limitations are a contributing factor to high attrition rates of drugs as a consequence of poor efficacy in clinical trials.
Original languageEnglish
Pages (from-to)44-50
JournalEuropean Pharmaceutical Review
Volume13
Issue number5
Publication statusPublished - 2008

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