Adenosine A(2A) agonists as therapy for glomerulonephritis

David A Ferenbach; Jeremy Hughes

doi:10.1038/ki.2011.167

Adenosine A(2A) agonists as therapy for glomerulonephritis

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Abstract / Description of output

Garcia et al. report the utility of pharmacological activation of the adenosine A(2A) receptor (A(2A)R) in preserving renal function, reversing fibrosis, and reducing macrophage infiltration and inflammatory activation in rat nephrotoxic nephritis. The role of A(2A)R activation in determining outcome in renal inflammation is discussed.

Original language	English
Pages (from-to)	329-31
Number of pages	3
Journal	Kidney International
Volume	80
Issue number	4
DOIs	https://doi.org/10.1038/ki.2011.167
Publication status	Published - 2011

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10.1038/ki.2011.167

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title = "Adenosine A(2A) agonists as therapy for glomerulonephritis",

abstract = "Garcia et al. report the utility of pharmacological activation of the adenosine A(2A) receptor (A(2A)R) in preserving renal function, reversing fibrosis, and reducing macrophage infiltration and inflammatory activation in rat nephrotoxic nephritis. The role of A(2A)R activation in determining outcome in renal inflammation is discussed.",

author = "Ferenbach, {David A} and Jeremy Hughes",

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journal = "Kidney International",

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AB - Garcia et al. report the utility of pharmacological activation of the adenosine A(2A) receptor (A(2A)R) in preserving renal function, reversing fibrosis, and reducing macrophage infiltration and inflammatory activation in rat nephrotoxic nephritis. The role of A(2A)R activation in determining outcome in renal inflammation is discussed.

U2 - 10.1038/ki.2011.167

DO - 10.1038/ki.2011.167

M3 - Article

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VL - 80

SP - 329

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JO - Kidney International

JF - Kidney International

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Adenosine A(2A) agonists as therapy for glomerulonephritis

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