Adenosine deaminase, Ada, is in mouse chromosome 2H3, and is not allelic with wasted, wst

C M Abbott, E P Evans, M Burtenshaw, S T Ball, C J Skidmore, J Jones, J Peters

Research output: Contribution to journalArticlepeer-review

Abstract

The adenosine deaminase locus (Ada) in the mouse has been localized by in situ hybridization to band 2H3. Linkage analysis of backcross data has shown that Ada is 13.8 +/- 2.7 cM from the coat texture mutant, ragged, Ra. From the results of earlier work (Abbott, C. M., et al., Proc. Natl. Acad. Sci. USA 83:693, 1986), it had been suggested that wst was a low-activity allele of Ada, but this cannot be so because Ada and wst have been found to be nonallelic.
Original languageEnglish
Pages (from-to)537-44
Number of pages8
JournalBiochemical genetics
Volume29
Issue number11-12
Publication statusPublished - 1991

Keywords

  • Adenosine Deaminase
  • Alleles
  • Animals
  • Chromosome Mapping
  • Crosses, Genetic
  • Genetic Linkage
  • Mice
  • Mice, Inbred C3H
  • Mice, Inbred C57BL
  • Mice, Mutant Strains
  • Nucleic Acid Hybridization

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