Adherens junctions connect stress fibres between adjacent endothelial cells

Jaime Millán; Robert J Cain; Natalia Reglero-Real; Carolina Bigarella; Beatriz Marcos-Ramiro; Laura Fernández-Martín; Isabel Correas; Anne J Ridley

doi:10.1186/1741-7007-8-11

Adherens junctions connect stress fibres between adjacent endothelial cells

Jaime Millán, Robert J Cain, Natalia Reglero-Real, Carolina Bigarella, Beatriz Marcos-Ramiro, Laura Fernández-Martín, Isabel Correas, Anne J Ridley

Deanery of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Endothelial cell-cell junctions maintain endothelial integrity and regulate vascular morphogenesis and homeostasis. Cell-cell junctions are usually depicted with a linear morphology along the boundaries between adjacent cells and in contact with cortical F-actin. However, in the endothelium, cell-cell junctions are highly dynamic and morphologically heterogeneous.

Original language	English
Journal	BMC Biology
Volume	8
DOIs	https://doi.org/10.1186/1741-7007-8-11
Publication status	Published - 2010

Keywords

Actins
Adherens Junctions
Cadherins
Cells, Cultured
Endothelial Cells
Focal Adhesions
Humans
Membrane Proteins
Microscopy, Electron, Transmission
Phosphoproteins
RNA, Small Interfering
Stress Fibers
Tumor Necrosis Factor-alpha
Zonula Occludens-1 Protein

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10.1186/1741-7007-8-11

Adherens junctions connect stress fibres between adjacent endothelial cells
© 2010 Millán et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Final published version, 21.3 MBLicence: Creative Commons: Attribution (CC-BY)

http://www.biomedcentral.com/1741-7007/8/11

Cite this

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title = "Adherens junctions connect stress fibres between adjacent endothelial cells",

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keywords = "Actins, Adherens Junctions, Cadherins, Cells, Cultured, Endothelial Cells, Focal Adhesions, Humans, Membrane Proteins, Microscopy, Electron, Transmission, Phosphoproteins, RNA, Small Interfering, Stress Fibers, Tumor Necrosis Factor-alpha, Zonula Occludens-1 Protein",

author = "Jaime Mill{\'a}n and Cain, {Robert J} and Natalia Reglero-Real and Carolina Bigarella and Beatriz Marcos-Ramiro and Laura Fern{\'a}ndez-Mart{\'i}n and Isabel Correas and Ridley, {Anne J}",

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T1 - Adherens junctions connect stress fibres between adjacent endothelial cells

AU - Millán, Jaime

AU - Cain, Robert J

AU - Reglero-Real, Natalia

AU - Bigarella, Carolina

AU - Marcos-Ramiro, Beatriz

AU - Fernández-Martín, Laura

AU - Correas, Isabel

AU - Ridley, Anne J

PY - 2010

Y1 - 2010

N2 - Endothelial cell-cell junctions maintain endothelial integrity and regulate vascular morphogenesis and homeostasis. Cell-cell junctions are usually depicted with a linear morphology along the boundaries between adjacent cells and in contact with cortical F-actin. However, in the endothelium, cell-cell junctions are highly dynamic and morphologically heterogeneous.

AB - Endothelial cell-cell junctions maintain endothelial integrity and regulate vascular morphogenesis and homeostasis. Cell-cell junctions are usually depicted with a linear morphology along the boundaries between adjacent cells and in contact with cortical F-actin. However, in the endothelium, cell-cell junctions are highly dynamic and morphologically heterogeneous.

KW - Actins

KW - Adherens Junctions

KW - Cadherins

KW - Cells, Cultured

KW - Endothelial Cells

KW - Focal Adhesions

KW - Humans

KW - Membrane Proteins

KW - Microscopy, Electron, Transmission

KW - Phosphoproteins

KW - RNA, Small Interfering

KW - Stress Fibers

KW - Tumor Necrosis Factor-alpha

KW - Zonula Occludens-1 Protein

U2 - 10.1186/1741-7007-8-11

DO - 10.1186/1741-7007-8-11

M3 - Article

C2 - 20122254

VL - 8

JO - BMC Biology

JF - BMC Biology

SN - 1741-7007

ER -

Adherens junctions connect stress fibres between adjacent endothelial cells

Abstract

Keywords

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