Adult mortality and probable cause of death in rural northern Malawi in the era of HIV treatment

Menard Chihana, Sian Floyd, Anna Molesworth, Amelia C Crampin, Ndoliwe Kayuni, Alison Price, Basia Zaba, Andreas Jahn, Hazzie Mvula, Albert Dube, Bagrey Ngwira, Judith R Glynn, Neil French

Research output: Contribution to journalArticlepeer-review

Abstract

Developing countries are undergoing demographic transition with a shift from high mortality caused by communicable diseases (CD) to lower mortality rates caused by non-communicable diseases (NCD). HIV/AIDS has disrupted this trend in sub-Saharan Africa. However, in recent years, HIV-associated mortality has been reduced with the introduction of widely available antiretroviral therapy (ART). Side effects of ART may lead to increased risk of cardiovascular diseases, raising the prospects of an accelerated transition towards NCD as the primary cause of death. We report population-based data to investigate changes in cause of death owing to NCD during the first 4 years after introduction of HIV treatment.
Original languageEnglish
Pages (from-to)e74-83
JournalTropical Medicine and International Health
Volume17
Issue number8
DOIs
Publication statusPublished - 2012

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