Adult mortality and probable cause of death in rural northern Malawi in the era of HIV treatment

Menard Chihana; Sian Floyd; Anna Molesworth; Amelia C Crampin; Ndoliwe Kayuni; Alison Price; Basia Zaba; Andreas Jahn; Hazzie Mvula; Albert Dube; Bagrey Ngwira; Judith R Glynn; Neil French

doi:10.1111/j.1365-3156.2012.02929.x

Adult mortality and probable cause of death in rural northern Malawi in the era of HIV treatment

Menard Chihana, Sian Floyd, Anna Molesworth, Amelia C Crampin, Ndoliwe Kayuni, Alison Price, Basia Zaba, Andreas Jahn, Hazzie Mvula, Albert Dube, Bagrey Ngwira, Judith R Glynn, Neil French

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Abstract / Description of output

Developing countries are undergoing demographic transition with a shift from high mortality caused by communicable diseases (CD) to lower mortality rates caused by non-communicable diseases (NCD). HIV/AIDS has disrupted this trend in sub-Saharan Africa. However, in recent years, HIV-associated mortality has been reduced with the introduction of widely available antiretroviral therapy (ART). Side effects of ART may lead to increased risk of cardiovascular diseases, raising the prospects of an accelerated transition towards NCD as the primary cause of death. We report population-based data to investigate changes in cause of death owing to NCD during the first 4 years after introduction of HIV treatment.

Original language	English
Pages (from-to)	e74-83
Journal	Tropical Medicine and International Health
Volume	17
Issue number	8
DOIs	https://doi.org/10.1111/j.1365-3156.2012.02929.x
Publication status	Published - 2012

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Adult mortality and probable cause of death in rural northern Malawi in the era of HIV treatmentFinal published version, 137 KB

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Chihana, M., Floyd, S., Molesworth, A., Crampin, A. C., Kayuni, N., Price, A., Zaba, B., Jahn, A., Mvula, H., Dube, A., Ngwira, B., Glynn, J. R., & French, N. (2012). Adult mortality and probable cause of death in rural northern Malawi in the era of HIV treatment. Tropical Medicine and International Health, 17(8), e74-83. https://doi.org/10.1111/j.1365-3156.2012.02929.x

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abstract = "Developing countries are undergoing demographic transition with a shift from high mortality caused by communicable diseases (CD) to lower mortality rates caused by non-communicable diseases (NCD). HIV/AIDS has disrupted this trend in sub-Saharan Africa. However, in recent years, HIV-associated mortality has been reduced with the introduction of widely available antiretroviral therapy (ART). Side effects of ART may lead to increased risk of cardiovascular diseases, raising the prospects of an accelerated transition towards NCD as the primary cause of death. We report population-based data to investigate changes in cause of death owing to NCD during the first 4 years after introduction of HIV treatment.",

author = "Menard Chihana and Sian Floyd and Anna Molesworth and Crampin, {Amelia C} and Ndoliwe Kayuni and Alison Price and Basia Zaba and Andreas Jahn and Hazzie Mvula and Albert Dube and Bagrey Ngwira and Glynn, {Judith R} and Neil French",

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T1 - Adult mortality and probable cause of death in rural northern Malawi in the era of HIV treatment

AU - Chihana, Menard

AU - Floyd, Sian

AU - Molesworth, Anna

AU - Crampin, Amelia C

AU - Kayuni, Ndoliwe

AU - Price, Alison

AU - Zaba, Basia

AU - Jahn, Andreas

AU - Mvula, Hazzie

AU - Dube, Albert

AU - Ngwira, Bagrey

AU - Glynn, Judith R

AU - French, Neil

PY - 2012

Y1 - 2012

N2 - Developing countries are undergoing demographic transition with a shift from high mortality caused by communicable diseases (CD) to lower mortality rates caused by non-communicable diseases (NCD). HIV/AIDS has disrupted this trend in sub-Saharan Africa. However, in recent years, HIV-associated mortality has been reduced with the introduction of widely available antiretroviral therapy (ART). Side effects of ART may lead to increased risk of cardiovascular diseases, raising the prospects of an accelerated transition towards NCD as the primary cause of death. We report population-based data to investigate changes in cause of death owing to NCD during the first 4 years after introduction of HIV treatment.

AB - Developing countries are undergoing demographic transition with a shift from high mortality caused by communicable diseases (CD) to lower mortality rates caused by non-communicable diseases (NCD). HIV/AIDS has disrupted this trend in sub-Saharan Africa. However, in recent years, HIV-associated mortality has been reduced with the introduction of widely available antiretroviral therapy (ART). Side effects of ART may lead to increased risk of cardiovascular diseases, raising the prospects of an accelerated transition towards NCD as the primary cause of death. We report population-based data to investigate changes in cause of death owing to NCD during the first 4 years after introduction of HIV treatment.

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DO - 10.1111/j.1365-3156.2012.02929.x

M3 - Article

C2 - 22943382

VL - 17

SP - e74-83

JO - Tropical Medicine and International Health

JF - Tropical Medicine and International Health

IS - 8

ER -

Adult mortality and probable cause of death in rural northern Malawi in the era of HIV treatment

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