Advances in dissecting mosquito innate immune responses to arbovirus infection

Rennos Fragkoudis, Ghassem Attarzadeh-Yazdi, Anthony A Nash, John K Fazakerley, Alain Kohl

Research output: Contribution to journalArticlepeer-review


Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signalling pathways, and cell death/apoptosis.
Original languageEnglish
Pages (from-to)2061-72
Number of pages12
JournalJournal of General Virology
Issue numberPt 9
Publication statusPublished - Sep 2009


  • Animals
  • Arbovirus Infections
  • Arboviruses
  • Culicidae
  • Humans
  • Immunity, Innate
  • Insect Vectors


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