Advances in dissecting mosquito innate immune responses to arbovirus infection

Rennos Fragkoudis; Ghassem Attarzadeh-Yazdi; Anthony A Nash; John K Fazakerley; Alain Kohl

doi:10.1099/vir.0.013201-0

Advances in dissecting mosquito innate immune responses to arbovirus infection

Rennos Fragkoudis, Ghassem Attarzadeh-Yazdi, Anthony A Nash, John K Fazakerley, Alain Kohl

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract

Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signalling pathways, and cell death/apoptosis.

Original language	English
Pages (from-to)	2061-72
Number of pages	12
Journal	Journal of General Virology
Volume	90
Issue number	Pt 9
DOIs	https://doi.org/10.1099/vir.0.013201-0
Publication status	Published - Sep 2009

Keywords

Animals
Arbovirus Infections
Arboviruses
Culicidae
Humans
Immunity, Innate
Insect Vectors

Access to Document

10.1099/vir.0.013201-0

Advances in dissecting mosquito innate immune responses to arbovirus infection
Available under Open Access
Final published version, 277 KB

http://vir.sgmjournals.org/content/90/9/2061

Cite this

@article{9c21bda1801341a7915d2e17947bde63,

title = "Advances in dissecting mosquito innate immune responses to arbovirus infection",

abstract = "Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signalling pathways, and cell death/apoptosis.",

keywords = "Animals, Arbovirus Infections, Arboviruses, Culicidae, Humans, Immunity, Innate, Insect Vectors",

author = "Rennos Fragkoudis and Ghassem Attarzadeh-Yazdi and Nash, {Anthony A} and Fazakerley, {John K} and Alain Kohl",

year = "2009",

month = sep,

doi = "10.1099/vir.0.013201-0",

language = "English",

volume = "90",

pages = "2061--72",

journal = "Journal of General Virology",

issn = "0022-1317",

publisher = "Society for General Microbiology ",

number = "Pt 9",

}

TY - JOUR

T1 - Advances in dissecting mosquito innate immune responses to arbovirus infection

AU - Fragkoudis, Rennos

AU - Attarzadeh-Yazdi, Ghassem

AU - Nash, Anthony A

AU - Fazakerley, John K

AU - Kohl, Alain

PY - 2009/9

Y1 - 2009/9

N2 - Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signalling pathways, and cell death/apoptosis.

AB - Arthropod-borne viruses - arboviruses - are a significant threat to public health. Whilst there is considerable knowledge about arbovirus interactions with vertebrate immunity, relatively little is known about how vectors such as mosquitoes control arbovirus infections. In this review, we discuss novel findings in the field of mosquito antiviral responses to arboviruses, in particular RNA interference, the up-and-coming field of general immune-signalling pathways, and cell death/apoptosis.

KW - Animals

KW - Arbovirus Infections

KW - Arboviruses

KW - Culicidae

KW - Humans

KW - Immunity, Innate

KW - Insect Vectors

U2 - 10.1099/vir.0.013201-0

DO - 10.1099/vir.0.013201-0

M3 - Article

C2 - 19570957

VL - 90

SP - 2061

EP - 2072

JO - Journal of General Virology

JF - Journal of General Virology

SN - 0022-1317

IS - Pt 9

ER -

Advances in dissecting mosquito innate immune responses to arbovirus infection

Abstract

Keywords

Access to Document

Fingerprint

Cite this