Advances in managing pregnancy toxaemia in sheep

James Crilly, Clare Phythian, Michael Evans

Research output: Contribution to journalArticlepeer-review


Ovine pregnancy toxaemia (OPT) is a metabolic disorder of ewes in late pregnancy. Cases are typically seen in ewes carrying multiple foetuses, hence the alternative name of “twin lamb disease”. The disease has been well-known for many years. Despite this, the toll inflicted by the disease remains considerable, due both to the poor prognosis of clinically affected animals, even with
appropriate treatment, and the impact of the provoking factors of undernutrition and concomitant disease on ewe morbidity, lamb survival and flock productivity. Cases of OPT are an indication of short-comings in the management of late-pregnancy ewes. In this article we will summarise the status of knowledge from extant reviews at the beginning, before delivering in more detail information drawn from studies published more recently.
Original languageEnglish
JournalIn Practice
Early online date5 Mar 2021
Publication statusE-pub ahead of print - 5 Mar 2021


  • Sheep
  • Herd health
  • Nutrition
  • Physiology
  • Metabolic diseases


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