Advancing full length genome sequencing for human RNA viral pathogens

Appolinaire Djikeng*, David Spiro

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In the face of numerous emerging and re-emerging viral threats, large-scale genome sequencing efforts are underway to monitor viral evolution in real-time. To fully appreciate the mechanisms of viral adaptation and evolution, and to also develop reagents and resources for a better molecular diagnosis of emerging and re-emerging viral infections, there has been an increasing effort toward producing full length viral genome sequences. To date, high-throughput platforms have been developed using traditional Sanger-based sequencing and there are currently prospects to apply next generation sequencing methods to develop an ultra high-throughput strategy for viral genome sequencing and analysis.

Original languageEnglish
Pages (from-to)47-53
Number of pages7
JournalFuture virology
Volume4
Issue number1
DOIs
Publication statusPublished - Jan 2009

Keywords

  • emerging and re-emerging viruses
  • genomics
  • human viruses
  • viral genome sequencing
  • viral infectious diseases
  • INFECTIOUS-DISEASES
  • VIRUS
  • METAGENOMICS
  • DISCOVERY
  • COMMUNITIES
  • REVEALS
  • LIBRARY

Cite this