Allergen immunotherapy for insect venom allergy: protocol for a systematic review

Sangeeta Dhami, Ulugbek Nurmatov, Eva-Maria Varga, Gunter Sturm, A. Muraro, Cezmi A Akdis, Dario Antolin-Amerigo, M Beatrice Bilò, Danijela Bokanovic, Moises A. Calderón, Ewa Cichocka-Jarosz, Joanna N.G. Oude Elberink, Radoslaw Gawlik, Thilo Jakob, Mitja Kosnik, Joanna Lange, Ervin Mingomataj, Dimitris I Mitsias, Holger Mosbech, Oliver PfaarConstantinos Pitsios, Valerio Pravettoni, Graham Roberts, Franziska Ruëff, Betül Ayşe Sin, Aziz Sheikh

Research output: Contribution to journalArticlepeer-review

Abstract

Background
The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for the Management of Insect Venom Allergy. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in the management of insect venom allergy.

Methods
We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised.

Discussion
The findings from this review will be used to inform the development of recomendations for EAACI’s Guidelines on AIT.
Original languageEnglish
JournalClinical and translational allergy
Volume6
Issue number6
DOIs
Publication statusPublished - 16 Feb 2016

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