AlphaSim: software package for simulating sequence

AlphaSim is a software package for simulating sequence, genotypic, phenotypic, and pedigree data in a wide range of population types (e.g., animal breeding, plant breeding, human genetics, natural populations). In developing AlphaSim major emphasis was placed on flexibility, computational efficiency, and ease of use. Populations can have almost any pedigree structure, almost any type of selection, a wide range of genotyping platforms, and multiple traits with a wide range of alternatives for genetic architecture. Additionally, AlphaSim also includes features for genome editing, manipulating the recombination rate and its genetic architecture, performing optimal contribution selection, and other “tricks”.