Alteration in lymphocyte responses, cytokine and chemokine profiles in chickens infected with genotype VII and VIII velogenic Newcastle disease virus

Mehdi Rasoli; Swee Keong Yeap; Sheau Wei Tan; Hassan Moeini; Aini Ideris; Mohd Hair Bejo; Noorjahan Banu Mohamed Alitheen; Pete Kaiser; Abdul Rahman Omar

doi:10.1016/j.cimid.2013.10.003

Alteration in lymphocyte responses, cytokine and chemokine profiles in chickens infected with genotype VII and VIII velogenic Newcastle disease virus

Mehdi Rasoli, Swee Keong Yeap, Sheau Wei Tan, Hassan Moeini, Aini Ideris, Mohd Hair Bejo, Noorjahan Banu Mohamed Alitheen, Pete Kaiser, Abdul Rahman Omar

Royal (Dick) School of Veterinary Studies

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Abstract / Description of output

Newcastle disease (ND) is a highly contagious avian disease and one of the major causes of economic losses in the poultry industry. The emergence of virulent NDV genotypes and repeated outbreaks of NDV in vaccinated chickens have raised the need for fundamental studies on the virus-host interactions. In this study, the profiles of B and T lymphocytes and macrophages and differential expression of 26 immune-related genes in the spleen of specific-pathogen-free (SPF) chickens, infected with either the velogenic genotype VII NDV strain IBS002 or the genotype VIII NDV strain AF2240, were evaluated. A significant reduction in T lymphocyte population and an increase in the infiltration of IgM(+) B cells and KUL01(+) macrophages were detected in the infected spleens at 1, 3 and 4 days post-infection (dpi) (P

Original language	English
Pages (from-to)	11-21
Journal	Comparative Immunology, Microbiology and Infectious Diseases
Volume	37
Issue number	1
Early online date	19 Oct 2013
DOIs	https://doi.org/10.1016/j.cimid.2013.10.003
Publication status	Published - 2014

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10.1016/j.cimid.2013.10.003

http://www.sciencedirect.com/science/article/pii/S0147957113000799

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Rasoli, M., Yeap, S. K., Tan, S. W., Moeini, H., Ideris, A., Bejo, M. H., Alitheen, N. B. M., Kaiser, P., & Omar, A. R. (2014). Alteration in lymphocyte responses, cytokine and chemokine profiles in chickens infected with genotype VII and VIII velogenic Newcastle disease virus. Comparative Immunology, Microbiology and Infectious Diseases, 37(1), 11-21. https://doi.org/10.1016/j.cimid.2013.10.003

@article{5173917b503d40a1ad946ca9739c2142,

title = "Alteration in lymphocyte responses, cytokine and chemokine profiles in chickens infected with genotype VII and VIII velogenic Newcastle disease virus",

abstract = "Newcastle disease (ND) is a highly contagious avian disease and one of the major causes of economic losses in the poultry industry. The emergence of virulent NDV genotypes and repeated outbreaks of NDV in vaccinated chickens have raised the need for fundamental studies on the virus-host interactions. In this study, the profiles of B and T lymphocytes and macrophages and differential expression of 26 immune-related genes in the spleen of specific-pathogen-free (SPF) chickens, infected with either the velogenic genotype VII NDV strain IBS002 or the genotype VIII NDV strain AF2240, were evaluated. A significant reduction in T lymphocyte population and an increase in the infiltration of IgM(+) B cells and KUL01(+) macrophages were detected in the infected spleens at 1, 3 and 4 days post-infection (dpi) (P",

author = "Mehdi Rasoli and Yeap, {Swee Keong} and Tan, {Sheau Wei} and Hassan Moeini and Aini Ideris and Bejo, {Mohd Hair} and Alitheen, {Noorjahan Banu Mohamed} and Pete Kaiser and Omar, {Abdul Rahman}",

note = "Pete Kaiser is supported by a Biotechnology and Biological Sciences Research Council Institute Strategic Programme Grant to The Roslin Institute.",

year = "2014",

doi = "10.1016/j.cimid.2013.10.003",

language = "English",

volume = "37",

pages = "11--21",

journal = "Comparative Immunology, Microbiology and Infectious Diseases",

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publisher = "Elsevier",

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}

Rasoli, M, Yeap, SK, Tan, SW, Moeini, H, Ideris, A, Bejo, MH, Alitheen, NBM, Kaiser, P & Omar, AR 2014, 'Alteration in lymphocyte responses, cytokine and chemokine profiles in chickens infected with genotype VII and VIII velogenic Newcastle disease virus', Comparative Immunology, Microbiology and Infectious Diseases, vol. 37, no. 1, pp. 11-21. https://doi.org/10.1016/j.cimid.2013.10.003

Alteration in lymphocyte responses, cytokine and chemokine profiles in chickens infected with genotype VII and VIII velogenic Newcastle disease virus. / Rasoli, Mehdi; Yeap, Swee Keong; Tan, Sheau Wei et al.
In: Comparative Immunology, Microbiology and Infectious Diseases, Vol. 37, No. 1, 2014, p. 11-21.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Alteration in lymphocyte responses, cytokine and chemokine profiles in chickens infected with genotype VII and VIII velogenic Newcastle disease virus

AU - Rasoli, Mehdi

AU - Yeap, Swee Keong

AU - Tan, Sheau Wei

AU - Moeini, Hassan

AU - Ideris, Aini

AU - Bejo, Mohd Hair

AU - Alitheen, Noorjahan Banu Mohamed

AU - Kaiser, Pete

AU - Omar, Abdul Rahman

N1 - Pete Kaiser is supported by a Biotechnology and Biological Sciences Research Council Institute Strategic Programme Grant to The Roslin Institute.

PY - 2014

Y1 - 2014

N2 - Newcastle disease (ND) is a highly contagious avian disease and one of the major causes of economic losses in the poultry industry. The emergence of virulent NDV genotypes and repeated outbreaks of NDV in vaccinated chickens have raised the need for fundamental studies on the virus-host interactions. In this study, the profiles of B and T lymphocytes and macrophages and differential expression of 26 immune-related genes in the spleen of specific-pathogen-free (SPF) chickens, infected with either the velogenic genotype VII NDV strain IBS002 or the genotype VIII NDV strain AF2240, were evaluated. A significant reduction in T lymphocyte population and an increase in the infiltration of IgM(+) B cells and KUL01(+) macrophages were detected in the infected spleens at 1, 3 and 4 days post-infection (dpi) (P

AB - Newcastle disease (ND) is a highly contagious avian disease and one of the major causes of economic losses in the poultry industry. The emergence of virulent NDV genotypes and repeated outbreaks of NDV in vaccinated chickens have raised the need for fundamental studies on the virus-host interactions. In this study, the profiles of B and T lymphocytes and macrophages and differential expression of 26 immune-related genes in the spleen of specific-pathogen-free (SPF) chickens, infected with either the velogenic genotype VII NDV strain IBS002 or the genotype VIII NDV strain AF2240, were evaluated. A significant reduction in T lymphocyte population and an increase in the infiltration of IgM(+) B cells and KUL01(+) macrophages were detected in the infected spleens at 1, 3 and 4 days post-infection (dpi) (P

U2 - 10.1016/j.cimid.2013.10.003

DO - 10.1016/j.cimid.2013.10.003

M3 - Article

C2 - 24225159

SN - 1878-1667

VL - 37

SP - 11

EP - 21

JO - Comparative Immunology, Microbiology and Infectious Diseases

JF - Comparative Immunology, Microbiology and Infectious Diseases

IS - 1

ER -

Alteration in lymphocyte responses, cytokine and chemokine profiles in chickens infected with genotype VII and VIII velogenic Newcastle disease virus

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