Tonic alertness was investigated in Alzheimer patients and normal elderly subjects. Sensitivity and criterion shifts were investigated across 45 min of continuous testing using a high event rate test with very low target probability. Alzheimer patients showed a significant sensitivity decrement over time that was unrelated to dementia severity. These results suggest that tonic alertness is impaired by Alzheimer's disease even in its early stages.
|Number of pages||10|
|Journal||Journal of clinical and experimental neuropsychology|
|Publication status||Published - 1994|