Ambulatory activity as an objective and quantifiable measure of non steroidal therapy

D.J. Walker, P.S. Heslop, Colin Chandler

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

OBJECTIVE:
To quantify any increase in short term spontaneous ambulatory activity resulting from the use of nonsteroidal antiinflammatory drugs (NSAID) in patients with rheumatoid arthritis (RA).
METHODS:
Double blind placebo controlled crossover study of 8 women with RA using conventional assessments and the Numact activity monitor.
RESULTS:
Patients' ambulatory activity was 50% greater during NSAID treatment compared to placebo treatment. Effect size calculated at 0.62, suggesting good sensitivity to change. The increased activity occurred late morning.
CONCLUSION:
Spontaneous ambulatory activity is an objective and relevant measure of disability.
Original languageEnglish
Pages (from-to)768-770
JournalThe Journal of rheumatology
Volume25
Issue number4
Publication statusPublished - 1998

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