This is the peer reviewed version of the following article: Zaiss, D.M.W. (2020), Amphiregulin as a driver of tissue fibrosis. Am J Transplant. doi:10.1111/ajt.15743, which has been published in final form at https://doi.org/10.1111/ajt.15743. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.