TY - JOUR
T1 - Amplification-free profiling of microRNA-122 biomarker in DILI patient serums, using the Luminex MAGPIX system
AU - Marín-Romero, Antonio
AU - Tabraue-Chávez, Mavys
AU - Dear, James W.
AU - Sánchez-Martín, Rosario M.
AU - Ilyine, Hugh
AU - Guardia-Monteagudo, Juan J.
AU - Fara, Mario A.
AU - López-Delgado, Francisco J.
AU - Díaz-Mochón, Juan J.
AU - Pernagallo, Salvatore
PY - 2020/6/29
Y1 - 2020/6/29
N2 - Dynamic chemical labelling is a single-base specific method to enable detection and quantification of micro-Ribonucleic Acids in biological fluids without extraction and pre-amplification. In this study, dynamic chemical labelling was combined with the Luminex MAGPIX system to profile levels of microRNA-122 biomarker in serum from patients with Drug-Induced Liver Injury.
AB - Dynamic chemical labelling is a single-base specific method to enable detection and quantification of micro-Ribonucleic Acids in biological fluids without extraction and pre-amplification. In this study, dynamic chemical labelling was combined with the Luminex MAGPIX system to profile levels of microRNA-122 biomarker in serum from patients with Drug-Induced Liver Injury.
U2 - 10.1016/j.talanta.2020.121265
DO - 10.1016/j.talanta.2020.121265
M3 - Article
SN - 0039-9140
VL - 219
JO - Talanta
JF - Talanta
M1 - 121265
ER -