An empirical analysis of domain adaptation algorithms for genomic sequence analysis

Gabriele Schweikert, Gunnar Rätsch, Christian Widmer, Bernhard Schölkopf

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We study the problem of domain transfer for a supervised classification task in mRNA splicing. We consider a number of recent domain transfer methods from machine learning, including some that are novel, and evaluate them on genomic sequence data from model organisms of varying evolutionary distance. We find that in cases where the organisms are not closely related, the use of domain adap-tation methods can help improve classification performance.
Original languageEnglish
Title of host publicationAdvances in Neural Information Processing Systems 21 (NIPS 2008)
PublisherMIT Press
Number of pages14
Publication statusPublished - 2008

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