Abstract
Purpose. To investigate whether the observed international differences in ROP treatment rates within the BOOST II trials might have been caused by international variation in ROP disease grading.
Methods. Groups of BOOST II trial ophthalmologists in UK, Australia and New Zealand (ANZ), and an international reference group (INT) used a web based system to grade a selection of RetCam images of ROP acquired during the BOOST II-UK trial. Rates of decisions to treat, plus disease grading, ROP stage grading, ROP zone grading, inter-observer variation within groups and intra-observer variation within groups were measured.
Methods. Groups of BOOST II trial ophthalmologists in UK, Australia and New Zealand (ANZ), and an international reference group (INT) used a web based system to grade a selection of RetCam images of ROP acquired during the BOOST II-UK trial. Rates of decisions to treat, plus disease grading, ROP stage grading, ROP zone grading, inter-observer variation within groups and intra-observer variation within groups were measured.
Original language | English |
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Journal | Eye |
Early online date | 28 Jul 2017 |
DOIs | |
Publication status | E-pub ahead of print - 28 Jul 2017 |