An investigation into the role of human papillomavirus in endobronchial papillary squamous tumours

F A Carey; D M Salter; K M Kerr; D Lamb

An investigation into the role of human papillomavirus in endobronchial papillary squamous tumours

F A Carey, D M Salter, K M Kerr, D Lamb

Research output: Contribution to journal › Article › peer-review

Abstract

Tissue specimens from 15 patients with endobronchial papillary squamous tumours were probed for the presence of human papillomavirus DNA using the technique of in situ hybridization with probes to human papillomavirus genotypes 4, 5, 6b, 8, 11, 16 and 18. Despite the histological similarity of these lesions to known human papillomavirus-associated tumours no evidence of hybridization was detected in any of the cases analysed. It is thus unlikely that human papillomavirus has a significant role in the genesis of these tumours.

Original language	English
Pages (from-to)	445-7
Number of pages	3
Journal	Respiratory Medicine
Volume	84
Issue number	6
Publication status	Published - Nov 1990

Keywords

Aged
Bronchial Neoplasms
Carcinoma, Papillary
Carcinoma, Squamous Cell
DNA Probes, HPV
DNA, Viral
Female
Humans
Male
Middle Aged
Nucleic Acid Hybridization
Papillomaviridae

Cite this

@article{f4b6a6bb26f9475e85012d5119f852d3,

title = "An investigation into the role of human papillomavirus in endobronchial papillary squamous tumours",

abstract = "Tissue specimens from 15 patients with endobronchial papillary squamous tumours were probed for the presence of human papillomavirus DNA using the technique of in situ hybridization with probes to human papillomavirus genotypes 4, 5, 6b, 8, 11, 16 and 18. Despite the histological similarity of these lesions to known human papillomavirus-associated tumours no evidence of hybridization was detected in any of the cases analysed. It is thus unlikely that human papillomavirus has a significant role in the genesis of these tumours.",

keywords = "Aged, Bronchial Neoplasms, Carcinoma, Papillary, Carcinoma, Squamous Cell, DNA Probes, HPV, DNA, Viral, Female, Humans, Male, Middle Aged, Nucleic Acid Hybridization, Papillomaviridae",

author = "Carey, {F A} and Salter, {D M} and Kerr, {K M} and D Lamb",

year = "1990",

month = nov,

language = "English",

volume = "84",

pages = "445--7",

journal = "Respiratory Medicine",

issn = "0954-6111",

publisher = "Elsevier",

number = "6",

}

TY - JOUR

T1 - An investigation into the role of human papillomavirus in endobronchial papillary squamous tumours

AU - Carey, F A

AU - Salter, D M

AU - Kerr, K M

AU - Lamb, D

PY - 1990/11

Y1 - 1990/11

N2 - Tissue specimens from 15 patients with endobronchial papillary squamous tumours were probed for the presence of human papillomavirus DNA using the technique of in situ hybridization with probes to human papillomavirus genotypes 4, 5, 6b, 8, 11, 16 and 18. Despite the histological similarity of these lesions to known human papillomavirus-associated tumours no evidence of hybridization was detected in any of the cases analysed. It is thus unlikely that human papillomavirus has a significant role in the genesis of these tumours.

AB - Tissue specimens from 15 patients with endobronchial papillary squamous tumours were probed for the presence of human papillomavirus DNA using the technique of in situ hybridization with probes to human papillomavirus genotypes 4, 5, 6b, 8, 11, 16 and 18. Despite the histological similarity of these lesions to known human papillomavirus-associated tumours no evidence of hybridization was detected in any of the cases analysed. It is thus unlikely that human papillomavirus has a significant role in the genesis of these tumours.

KW - Aged

KW - Bronchial Neoplasms

KW - Carcinoma, Papillary

KW - Carcinoma, Squamous Cell

KW - DNA Probes, HPV

KW - DNA, Viral

KW - Female

KW - Humans

KW - Male

KW - Middle Aged

KW - Nucleic Acid Hybridization

KW - Papillomaviridae

M3 - Article

C2 - 2177215

VL - 84

SP - 445

EP - 447

JO - Respiratory Medicine

JF - Respiratory Medicine

SN - 0954-6111

IS - 6

ER -

An investigation into the role of human papillomavirus in endobronchial papillary squamous tumours

Abstract

Keywords

Fingerprint

Cite this