An investigation of the effectiveness of testosterone implants in combination with the prolactin inhibitor quinagolide in the suppression of spermatogenesis in men

W Morton Hair, Frederick C W Wu, Gerald A Lincoln

Research output: Contribution to journalArticlepeer-review

Abstract

Administration of testosterone inhibits gonadotrophin secretion and spermatogenesis in men but the degree of response is highly variable. This treatment also stimulates prolactin, itself a progonadal hormone in animals. This study investigated whether concomitant suppression of prolactin (PRL) with the non-ergot, dopamine receptor agonist quinagolide (Q), would enhance the efficacy of testosterone in its inhibition of spermatogenesis in healthy eugonadal men.
Original languageEnglish
Pages (from-to)749-55
Number of pages7
JournalHuman Reproduction
Volume18
Issue number4
Publication statusPublished - 2003

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