An update on equine postoperative ileus: Definitions, pathophysiology and management.

Zofia Lisowski, Robert Pirie, Anthony Blikslager, Dominique Lefebvre, David Hume, Neil Hudson

Research output: Contribution to journalArticlepeer-review

Abstract

Postoperative ileus (POI) is a serious condition which any horse undergoing abdominal surgery is at risk of developing, leading to increased hospitalisation time and resulting costs. Advances in the understanding of the development of equine POI are mainly based on human and rodent
literature, where manipulation-induced inflammation has been identified as a key trigger, with activation of resident muscularis externa macrophages playing a crucial role in the pathophysiology. Despite many pharmacological trials in all species, there is no single completely successful treatment for POI, highlighting that the condition is multifactorial in cause and requires a multimodal approach to minimise its incidence.
Original languageEnglish
Pages (from-to)292-303
JournalEquine Veterinary Journal
Volume50
Issue number3
Early online date29 Jan 2018
DOIs
Publication statusPublished - May 2018

Keywords

  • horse
  • colic
  • SURGERY
  • postoperative ileus
  • abdomen
  • gastrointestinal motility

Fingerprint

Dive into the research topics of 'An update on equine postoperative ileus: Definitions, pathophysiology and management.'. Together they form a unique fingerprint.

Cite this