The anaplastic lymphoma kinase (ALK) receptor tyrosine kinase is now implicated in a wide range of human cancers. Results from recent clinical trials with ALK inhibitors provide promise for patients harboring oncogenic ALK lesions. This review will discuss our current understanding of ALK in human cancer and the implication of recent results for treatment.
|Number of pages||21|
|Journal||Critical Review in Oncogenesis|
|Publication status||Published - 2012|
- Protein Kinase Inhibitors
- Receptor Protein-Tyrosine Kinases