TY - JOUR
T1 - Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent
AU - Verdugo, Marta Pereira
AU - Mullin, Victoria E.
AU - Scheu, Amelie
AU - Mattiangeli, Valeria
AU - Daly, Kevin G.
AU - Maisano Delser, Pierpaolo
AU - Hare, Andrew J.
AU - Burger, Joachim
AU - Collins, Matthew J.
AU - Kehati, Ron
AU - Hesse, Paula
AU - Fulton, Deirdre
AU - Sauer, Eberhard W.
AU - Mohaseb, Fatemeh A.
AU - Davoudi, Hossein
AU - Khazaeli, Roya
AU - Lhuillier, Johanna
AU - Rapin, Claude
AU - Ebrahimi, Saeed
AU - Khasanov, Mutalib
AU - Vahidi, S. M. Farhad
AU - MacHugh, David E.
AU - Ertuğrul, Okan
AU - Koukouli-Chrysanthaki, Chaido
AU - Sampson, Adamantios
AU - Kazantzis, George
AU - Kontopoulos, Ioannis
AU - Bulatovic, Jelena
AU - Stojanović, Ivana
AU - Mikdad, Abdesalam
AU - Benecke, Norbert
AU - Linstädter, Jörg
AU - Sablin, Mikhail
AU - Bendrey, Robin
AU - Gourichon, Lionel
AU - Arbuckle, Benjamin S.
AU - Mashkour, Marjan
AU - Orton, David
AU - Horwitz, Liora Kolska
AU - Teasdale, Matthew D.
AU - Bradley, Daniel G.
PY - 2019/7/12
Y1 - 2019/7/12
N2 - Cattle were domesticated ∼10,000 years ago, but analysis of modern breeds has not elucidated their origins. Verdugo et al. performed genome-wide analysis of 67 ancient Near Eastern Bos taurus DNA samples. Several populations of ancient aurochs were progenitors of domestic cows. These genetic lineages mixed ∼4000 years ago in a region around the Indus Valley. Interestingly, mitochondrial analysis indicated that genetic material likely derived from arid-adapted Bos indicus (zebu) bulls was introduced by introgression.Science, this issue p. 173Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, ~4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.
AB - Cattle were domesticated ∼10,000 years ago, but analysis of modern breeds has not elucidated their origins. Verdugo et al. performed genome-wide analysis of 67 ancient Near Eastern Bos taurus DNA samples. Several populations of ancient aurochs were progenitors of domestic cows. These genetic lineages mixed ∼4000 years ago in a region around the Indus Valley. Interestingly, mitochondrial analysis indicated that genetic material likely derived from arid-adapted Bos indicus (zebu) bulls was introduced by introgression.Science, this issue p. 173Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, ~4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.
U2 - 10.1126/science.aav1002
DO - 10.1126/science.aav1002
M3 - Article
VL - 365
JO - Science
JF - Science
SN - 0036-8075
IS - 6449
ER -