Animal models of cystic fibrosis

Bob J Scholte, Donald J Davidson, Martina Wilke, Hugo R De Jonge

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Animal models of cystic fibrosis, in particular several different mutant mouse strains obtained by homologous recombination, have contributed considerably to our understanding of CF pathology. In this review, we describe and compare the main phenotypic features of these models. Recent and possible future developments in this field are discussed.

Original languageEnglish
Pages (from-to)183-90
Number of pages8
JournalJournal of Cystic Fibrosis
Volume3 Suppl 2
Publication statusPublished - Aug 2004

Keywords / Materials (for Non-textual outputs)

  • Animals
  • Cystic Fibrosis
  • Ferrets
  • Mice
  • Models, Animal
  • Mutation
  • Phenotype
  • Sheep
  • Swine


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