Application of gene expression profiling to cardiovascular disease

P A Henriksen, Y Kotelevtsev

Research output: Contribution to journalReview articlepeer-review

Abstract

The number of cardiovascular publications featuring gene expression profiling technologies is growing rapidly. This article introduces four profiling techniques; serial analysis of gene expression, differential display, subtractive hybridisation and DNA microarrays. Illustrations of their application towards cardiovascular research are given and their potential for gene discovery and improving our understanding of gene function is discussed.

Original languageEnglish
Pages (from-to)16-24
Number of pages9
JournalCardiovascular Research
Volume54
Issue number1
Publication statusPublished - Apr 2002

Keywords

  • Animals
  • Cardiovascular Diseases/embryology
  • Cells, Cultured
  • Gene Expression Profiling
  • Humans
  • Image Processing, Computer-Assisted
  • Models, Animal
  • Myocardium/metabolism
  • Oligonucleotide Array Sequence Analysis
  • Reverse Transcriptase Polymerase Chain Reaction

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