Area-based socioeconomic status, type 2 diabetes and cardiovascular mortality in Scotland

Scottish Diabet Res Network SDRN, Caroline Jackson, N. R. V. Jones, J. J. Walker, Colin Fischbacher, H. M. Colhoun, G. P. Leese, R. S. Lindsay, J. A. McKnight, Andrew Morris, J. R. Petrie, N. Sattar, S. H. Wild

Research output: Contribution to journalArticlepeer-review

Abstract

Aims/hypothesis
The aim of this study was to explore the relationships between type 2 diabetes mellitus, area-based socioeconomic status (SES) and cardiovascular disease mortality in Scotland.
Methods We used an area-based measure of SES, Scottish national diabetes register data linked to mortality records, and general population cause-specific mortality data to investigate the relationships between SES, type 2 diabetes and mortality from ischaemic heart disease (IHD) and cerebrovascular disease (CbVD), for 2001–2007. We used negative binomial regression to obtain age-adjusted RRs of mortality (by sex), comparing people with type 2 diabetes with the non-diabetic population. Results
Among 216,652 people aged 40years or older with type 2 diabetes (980,687person-years), there were 10,554 IHD deaths and 4,378 CbVD deaths. Age-standardised mortality increased with increasing deprivation, and was higher among men. IHD mortality RRs were highest among the least deprived quintile and lowest in the most deprived quintile (men: least deprived, RR 1.94 [95% CI 1.61, 2.33]; most deprived, RR 1.46 [95% CI 1.23, 1.74]) and were higher in women than men (women: least deprived, RR 2.84 [95% CI 2.12, 3.80]; most deprived, RR 2.04 [95% CI 1.55, 2.69]). A similar, weaker, pattern was observed for cerebrovascular mortality.
Conclusions/interpretation Absolute risk of cardiovascular mortality is higher in people with diabetes than in the non-diabetic population and increases with increasing deprivation. The relative impact of diabetes on cardiovascular mortality differs by SES, and further efforts to reduce cardiovascular risk both in deprived groups and people with diabetes are required. Prevention of diabetes may reduce socioeconomic health inequalities.

Original languageEnglish
Pages (from-to)2938-2945
Number of pages8
JournalDiabetologia
Volume55
Issue number11
DOIs
Publication statusPublished - Nov 2012

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