Aspirin use in middle-aged men with cardiovascular disease: Are opportunities being missed?

A. K. McCallum*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Background. Since the 1980s, clinical trial evidence has supported aspirin use in the secondary prevention of cardiovascular disease (CVD). Aim. To explore aspirin use among British men with known CVD in a population-based study. Method Longitudinal study (British Regional Heart Study), in which subjects have been followed up for cardiovascular morbidity and mortality since 1978-1980. Aspirin use was assessed by questionnaires to study participants in November 1992 (Q92); cardiovascular diagnoses are based on general practice notifications to October 1992. A total of 5751 men aged 52-73 years (87% of survivors) completed questions on aspirin use. Results. Overall, 547 men (9.5%) were taking aspirin daily, of whom 321 (59%) had documented CVD. Among men with pre-existing disease, 153 out of 345 (44%) men with myocardial infarction, 42 out of 109 (39%) with stroke, and 75 out of 247 (29%) with angina were taking aspirin daily. Among men with angina (54% versus 26%) or myocardial infarction (59% versus 42%), those who had undergone coronary artery bypass surgery (CABG) or angioplasty were more likely to be receiving aspirin. Higher rates of aspirin use were also found in those whose last major event occurred after January 1990 (47% versus (34%). There was no association between aspirin use and social class or region of residence. Conclusion. Despite strong evidence of its effectiveness, many patients with established CVD were not receiving aspirin. Daily aspirin treatment was less likely in men with less recent major CVD events and in those who had not received invasive treatment.

Original languageEnglish
Pages (from-to)417-421
Number of pages5
JournalBritish Journal of General Practice
Issue number420
Publication statusPublished - 1997

Keywords / Materials (for Non-textual outputs)

  • Aspririn
  • Cardiovascular disease
  • Longitudinal study


Dive into the research topics of 'Aspirin use in middle-aged men with cardiovascular disease: Are opportunities being missed?'. Together they form a unique fingerprint.

Cite this