Assessment of additional endpoints for trials in acute stroke - what, when, where, in who?

European Stroke Organisation Outcomes Working Group, Peter D Schellinger, Philip M W Bath, Kennedy R Lees, Natan M Bornstein, Eitan Uriel, Wolfgang Eisert, Didier Leys

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Functional outcome in acute stroke trials among others is usually measured on the modified Rankin Scale. However, new onset of depression, cognitive decline, and communication deficits alone or in combination affect more than 25% of patients. This report summarizes the findings and conclusions of a workshop by the European Stroke Organization held in February 2011 We propose that assessment of mood disorders, cognitive impairment/dementia, language or communication dysfunction, and quality of life should supplement outcome measures after acute stroke.

Original languageEnglish
Pages (from-to)227-30
Number of pages4
JournalInternational Journal of Stroke
Volume7
Issue number3
DOIs
Publication statusPublished - 9 Mar 2012
Externally publishedYes

Keywords / Materials (for Non-textual outputs)

  • Clinical Trials as Topic
  • Cognition Disorders
  • Depression
  • Endpoint Determination
  • Humans
  • Mood Disorders
  • Quality of Life
  • Stroke
  • Journal Article

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