Assessment of Spectral Doppler in Preclinical Ultrasound Using a Small-Size Rotating Phantom

Xin Yang, Chao Sun, Tom Anderson, Carmel M Moran, Patrick W F Hadoke, Gillian A Gray, Peter R Hoskins

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Preclinical ultrasound scanners are used to measure blood flow in small animals, but the potential errors in blood velocity measurements have not been quantified. This investigation rectifies this omission through the design and use of phantoms and evaluation of measurement errors for a preclinical ultrasound system (Vevo 770, Visualsonics, Toronto, ON, Canada). A ray model of geometric spectral broadening was used to predict velocity errors. A small-scale rotating phantom, made from tissue-mimicking material, was developed. True and Doppler-measured maximum velocities of the moving targets were compared over a range of angles from 10° to 80°. Results indicate that the maximum velocity was overestimated by up to 158% by spectral Doppler. There was good agreement (50%). The phantom is capable of validating the performance of blood velocity measurement in preclinical ultrasound.
Original languageEnglish
Pages (from-to)1491-1499
Number of pages9
JournalUltrasound in Medicine and Biology (UMB)
Issue number8
Early online date24 May 2013
Publication statusPublished - Aug 2013


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