TY - JOUR
T1 - Association between apolipoprotein E genotype and carotid intima-media thickness may suggest a specific effect on large artery atherothrombotic stroke
AU - Paternoster, Lavinia
AU - Martínez González, Nahara Anáni
AU - Lewis, Stephanie
AU - Sudlow, Cathie
PY - 2008
Y1 - 2008
N2 - Apolipoprotein E genotype (APOE) influences cholesterol levels and ischemic heart disease. Although there is no convincing overall association with ischemic stroke, APOE may influence large artery (atherothrombotic) stroke, for which carotid intima-media thickness (CIMT) is an informative intermediate phenotype. We therefore performed a systematic review and meta-analysis of the association between APOE and CIMT.
AB - Apolipoprotein E genotype (APOE) influences cholesterol levels and ischemic heart disease. Although there is no convincing overall association with ischemic stroke, APOE may influence large artery (atherothrombotic) stroke, for which carotid intima-media thickness (CIMT) is an informative intermediate phenotype. We therefore performed a systematic review and meta-analysis of the association between APOE and CIMT.
U2 - 10.1161/STROKEAHA.107.488866
DO - 10.1161/STROKEAHA.107.488866
M3 - Article
C2 - 18063831
SN - 1524-4628
VL - 39
SP - 48
EP - 54
JO - Stroke; a journal of cerebral circulation
JF - Stroke; a journal of cerebral circulation
IS - 1
ER -