Association between diabetes mellitus and incidence and case-fatality after stroke due to intracerebral haemorrhage: a retrospective population-based cohort study

Marion Boulanger, Rustam Salman, Jan Kerssens, Sarah Wild

Research output: Contribution to journalArticlepeer-review

Abstract

We investigated the associations between types of diabetes and ICH incidence and case-fatality after ICH, in a retrospective cohort study of people aged 40-89 years in Scotland 2004-2013 using linkage of population-based records of diagnosed diabetes, hospital discharges and deaths. We calculated ICH incidence and 30-day case-fatality after hospital admission for ICH and their relative risks (RR) and 95% confidence intervals (95%CI) for people with type 1 or type 2 diabetes compared to people without diabetes adjusting for age, sex and socio-economic status (SES). There were 77, 1275 and 9778 incident ICH and case-fatality (95% CI) was 44 (33, 57)%, 38 (35, 41)% and 36% (35, 37)% in people with type 1, type 2 and without diabetes, respectively. In comparison to the non-diabetic population, type 1 diabetes was associated with a higher incidence of ICH (1.74, 95%CI 1.38-2.21) and case-fatality after ICH (1.35, 95%CI 1.01-1.70), after adjustment for age, sex and SES. Small increases in ICH incidence 1.06, 95%CI 0.99-1.12) and case-fatality 1.04, 95%CI 0.96-1.13) in people with type 2 diabetes compared to non-diabetic people were not statistically significant.
Original languageEnglish
JournalDiabetes, Obesity and Metabolism
Early online date9 Mar 2017
DOIs
Publication statusE-pub ahead of print - 9 Mar 2017

Keywords

  • Case-fatality
  • Epidemiology
  • Haemorrhagic stroke
  • Incidence
  • Intracerebral

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