Association between smoking, outcomes, and early clopidogrel use in patients with acute coronary syndrome: insights from the Global Registry of Acute Coronary Events

Matthew Sibbald, Andrew T Yan, Wei Huang, Keith A A Fox, Joel M Gore, Ph Gabriel Steg, Kim A Eagle, David Brieger, Gilles Montalescot, Shaun G Goodman

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Smoking induces CYP1A2, thereby enhancing clopidogrel conversion to its active metabolite. We sought to determine the association between clopidogrel use and clinical outcomes in smokers versus nonsmokers with a broad spectrum of acute coronary syndrome (ACS).
Original languageEnglish
Pages (from-to)855-61
Number of pages7
JournalAmerican Heart Journal
Volume160
Issue number5
DOIs
Publication statusPublished - 2010

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