Association between smoking, outcomes, and early clopidogrel use in patients with acute coronary syndrome: insights from the Global Registry of Acute Coronary Events

Matthew Sibbald, Andrew T Yan, Wei Huang, Keith A A Fox, Joel M Gore, Ph Gabriel Steg, Kim A Eagle, David Brieger, Gilles Montalescot, Shaun G Goodman

Research output: Contribution to journalArticlepeer-review

Abstract

Smoking induces CYP1A2, thereby enhancing clopidogrel conversion to its active metabolite. We sought to determine the association between clopidogrel use and clinical outcomes in smokers versus nonsmokers with a broad spectrum of acute coronary syndrome (ACS).
Original languageEnglish
Pages (from-to)855-61
Number of pages7
JournalAmerican Heart Journal
Volume160
Issue number5
DOIs
Publication statusPublished - 2010

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