Association of KIBRA and memory

T. C. Bates; Jackie Price; Sarah Harris; Riccardo E Marioni; F. G. R. Fowkes; Marlene Stewart; G. D. Murray; L. J. Whalley; John Starr; I. J. Deary

doi:10.1016/j.neulet.2009.04.050

Association of KIBRA and memory

T. C. Bates, Jackie Price, Sarah Harris, Riccardo E Marioni, F. G. R. Fowkes, Marlene Stewart, G. D. Murray, L. J. Whalley, John Starr, I. J. Deary

Research output: Contribution to journal › Article › peer-review

Abstract

We report on the association of KIBRA with memory in two samples of older individuals assessed on either memory for semantically unrelated word stimuli (Rey Auditory Verbal Learning Test, n = 2091). or a measure of semantically related material (the WAIS Logical Memory Test of prose-passage recall, n = 542). SNP rs17070145 was associated with delayed recall of semantically unrelated items, but not with immediate recall for these stimuli, nor with either immediate or delayed recall for semantically related material. The pattern of results suggests a role for the T -> C substitution in intron 9 of KIBRA in a component of episodic memory involved in long-term storage but independent of processes shared with immediate recall such as rehearsal involved in acquisition and rehearsal or processes. (C) 2009 Published by Elsevier Ireland Ltd.

Original language	English
Pages (from-to)	140-143
Number of pages	4
Journal	Neuroscience Letters
Volume	458
Issue number	3
DOIs	https://doi.org/10.1016/j.neulet.2009.04.050
Publication status	Published - 2009

Keywords / Materials (for Non-textual outputs)

memory

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10.1016/j.neulet.2009.04.050

Cite this

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title = "Association of KIBRA and memory",

abstract = "We report on the association of KIBRA with memory in two samples of older individuals assessed on either memory for semantically unrelated word stimuli (Rey Auditory Verbal Learning Test, n = 2091). or a measure of semantically related material (the WAIS Logical Memory Test of prose-passage recall, n = 542). SNP rs17070145 was associated with delayed recall of semantically unrelated items, but not with immediate recall for these stimuli, nor with either immediate or delayed recall for semantically related material. The pattern of results suggests a role for the T -> C substitution in intron 9 of KIBRA in a component of episodic memory involved in long-term storage but independent of processes shared with immediate recall such as rehearsal involved in acquisition and rehearsal or processes. (C) 2009 Published by Elsevier Ireland Ltd.",

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year = "2009",

doi = "10.1016/j.neulet.2009.04.050",

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volume = "458",

pages = "140--143",

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T1 - Association of KIBRA and memory

AU - Bates, T. C.

AU - Price, Jackie

AU - Harris, Sarah

AU - Marioni, Riccardo E

AU - Fowkes, F. G. R.

AU - Stewart, Marlene

AU - Murray, G. D.

AU - Whalley, L. J.

AU - Starr, John

AU - Deary, I. J.

PY - 2009

Y1 - 2009

N2 - We report on the association of KIBRA with memory in two samples of older individuals assessed on either memory for semantically unrelated word stimuli (Rey Auditory Verbal Learning Test, n = 2091). or a measure of semantically related material (the WAIS Logical Memory Test of prose-passage recall, n = 542). SNP rs17070145 was associated with delayed recall of semantically unrelated items, but not with immediate recall for these stimuli, nor with either immediate or delayed recall for semantically related material. The pattern of results suggests a role for the T -> C substitution in intron 9 of KIBRA in a component of episodic memory involved in long-term storage but independent of processes shared with immediate recall such as rehearsal involved in acquisition and rehearsal or processes. (C) 2009 Published by Elsevier Ireland Ltd.

AB - We report on the association of KIBRA with memory in two samples of older individuals assessed on either memory for semantically unrelated word stimuli (Rey Auditory Verbal Learning Test, n = 2091). or a measure of semantically related material (the WAIS Logical Memory Test of prose-passage recall, n = 542). SNP rs17070145 was associated with delayed recall of semantically unrelated items, but not with immediate recall for these stimuli, nor with either immediate or delayed recall for semantically related material. The pattern of results suggests a role for the T -> C substitution in intron 9 of KIBRA in a component of episodic memory involved in long-term storage but independent of processes shared with immediate recall such as rehearsal involved in acquisition and rehearsal or processes. (C) 2009 Published by Elsevier Ireland Ltd.

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U2 - 10.1016/j.neulet.2009.04.050

DO - 10.1016/j.neulet.2009.04.050

M3 - Article

SN - 0304-3940

VL - 458

SP - 140

EP - 143

JO - Neuroscience Letters

JF - Neuroscience Letters

IS - 3

ER -

Association of KIBRA and memory

Abstract

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A Hundred at Ninety: the common cause Hypothesis of Ageing tested in four waves of the Lothian Birth Cohort 1921

A genome wide association study of non pathological cognitive ageing

MRC Centre for Cognitive Ageing and Cognitive Epidemiology

Cite this

Association of KIBRA and memory

Abstract

Keywords / Materials (for Non-textual outputs)

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Projects

A Hundred at Ninety: the common cause Hypothesis of Ageing tested in four waves of the Lothian Birth Cohort 1921

A genome wide association study of non pathological cognitive ageing

MRC Centre for Cognitive Ageing and Cognitive Epidemiology

Cite this