Asymmetric resolution and molecular recognition. Part 2. The X-ray crystal structures of ephedrine-N-benzyloxycarbonyl-L-leucine and ephedrine-N-acetyl-L- valine

Ann Gorman, Robert O. Gould, Alexandra M. Gray, Paul Taylor, Malcolm D. Walkinshaw*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The crystal structures of ephedrine-N-benzyloxycarbonyl-L-leucine (1) (P212121, a = 14.067, b = 29.982, c = 5.737 Å) and ephedrine-N-acetyl-L-valine monohydrate (2) (P212 121, a = 13.501, b = 19.173, c = 7.694 A) are reported and the conformations of the ephedrine moieties are compared with those in other structures. Charge-charge interactions, hydrogen bonding, and specific phenyl-phenyl interactions play a part in these stereospecific crystallisations.

Original languageEnglish
Pages (from-to)739-746
Number of pages8
JournalJournal of the Chemical Society, Perkin Transactions 2
Issue number5
DOIs
Publication statusPublished - 1 Jan 1986

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