Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk

Nicola Pirastu; Peter K Joshi; Paul S de Vries; Marilyn C Cornelis; Paul M McKeigue; NaNa Keum; Nora Franceschini; Marco Colombo; Edward L Giovannucci; Athina Spiliopoulou; Lude Franke; Kari E North; Peter Kraft; Alanna C Morrison; Tõnu Esko; James F Wilson

doi:10.1038/s41467-018-04857-7

Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk

Nicola Pirastu, Peter K Joshi, Paul S de Vries, Marilyn C Cornelis, Paul M McKeigue, NaNa Keum, Nora Franceschini, Marco Colombo, Edward L Giovannucci, Athina Spiliopoulou, Lude Franke, Kari E North, Peter Kraft, Alanna C Morrison, Tõnu Esko, James F Wilson

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Abstract / Description of output

We have been alerted that in our recent Article the calculations used to transform the heritability from the observed scale to the liability scale did not take into account the individuals in category 2 of the baldness scale, who were removed in our original analysis. This led to an overestimation of the heritability on the liability scale, which should have been 0.62 instead of 0.94. Moreover, in the Title and in the Abstract, we report that we can explain 38% of the risk, while in fact that is the proportion of heritability explained by the loci we discovered. These errors do not substantially change the paper or its conclusions apart from the statement MBP is therefore probably one of the most heritable complex traits. Genome-wide significant associations and pathway analyses are not affected in any way and male-pattern baldness remains less genetically complex than other complex traits. We wish to thank Yap et al. for bringing this to our attention.

Original language	English
Pages (from-to)	2536
Journal	Nature Communications
Volume	9
Issue number	1
DOIs	https://doi.org/10.1038/s41467-018-04857-7
Publication status	Published - 29 Jun 2018

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10.1038/s41467-018-04857-7

Author Correction - GWAS for male-pattern baldness...
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1 Article

GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk
Pirastu, N., Joshi, P. K., de Vries, P. S., Cornelis, M. C., McKeigue, P. M., Keum, N., Franceschini, N., Colombo, M., Giovannucci, E. L., Spiliopoulou, A., Franke, L., North, K. E., Kraft, P., Morrison, A. C., Esko, T. & Wilson, J. F., 17 Nov 2017, In: Nature Communications. 8, 1584.
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Pirastu, N., Joshi, P. K., de Vries, P. S., Cornelis, M. C., McKeigue, P. M., Keum, N., Franceschini, N., Colombo, M., Giovannucci, E. L., Spiliopoulou, A., Franke, L., North, K. E., Kraft, P., Morrison, A. C., Esko, T., & Wilson, J. F. (2018). Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. Nature Communications, 9(1), 2536. https://doi.org/10.1038/s41467-018-04857-7

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title = "Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk",

abstract = "We have been alerted that in our recent Article the calculations used to transform the heritability from the observed scale to the liability scale did not take into account the individuals in category 2 of the baldness scale, who were removed in our original analysis. This led to an overestimation of the heritability on the liability scale, which should have been 0.62 instead of 0.94. Moreover, in the Title and in the Abstract, we report that we can explain 38% of the risk, while in fact that is the proportion of heritability explained by the loci we discovered. These errors do not substantially change the paper or its conclusions apart from the statement MBP is therefore probably one of the most heritable complex traits. Genome-wide significant associations and pathway analyses are not affected in any way and male-pattern baldness remains less genetically complex than other complex traits. We wish to thank Yap et al. for bringing this to our attention.",

keywords = "Published Erratum",

author = "Nicola Pirastu and Joshi, {Peter K} and {de Vries}, {Paul S} and Cornelis, {Marilyn C} and McKeigue, {Paul M} and NaNa Keum and Nora Franceschini and Marco Colombo and Giovannucci, {Edward L} and Athina Spiliopoulou and Lude Franke and North, {Kari E} and Peter Kraft and Morrison, {Alanna C} and T{\~o}nu Esko and Wilson, {James F}",

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Pirastu, N, Joshi, PK, de Vries, PS, Cornelis, MC, McKeigue, PM, Keum, N, Franceschini, N, Colombo, M, Giovannucci, EL, Spiliopoulou, A, Franke, L, North, KE, Kraft, P, Morrison, AC, Esko, T & Wilson, JF 2018, 'Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk', Nature Communications, vol. 9, no. 1, pp. 2536. https://doi.org/10.1038/s41467-018-04857-7

TY - JOUR

T1 - Author Correction

T2 - GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk

AU - Pirastu, Nicola

AU - Joshi, Peter K

AU - de Vries, Paul S

AU - Cornelis, Marilyn C

AU - McKeigue, Paul M

AU - Keum, NaNa

AU - Franceschini, Nora

AU - Colombo, Marco

AU - Giovannucci, Edward L

AU - Spiliopoulou, Athina

AU - Franke, Lude

AU - North, Kari E

AU - Kraft, Peter

AU - Morrison, Alanna C

AU - Esko, Tõnu

AU - Wilson, James F

PY - 2018/6/29

Y1 - 2018/6/29

N2 - We have been alerted that in our recent Article the calculations used to transform the heritability from the observed scale to the liability scale did not take into account the individuals in category 2 of the baldness scale, who were removed in our original analysis. This led to an overestimation of the heritability on the liability scale, which should have been 0.62 instead of 0.94. Moreover, in the Title and in the Abstract, we report that we can explain 38% of the risk, while in fact that is the proportion of heritability explained by the loci we discovered. These errors do not substantially change the paper or its conclusions apart from the statement MBP is therefore probably one of the most heritable complex traits. Genome-wide significant associations and pathway analyses are not affected in any way and male-pattern baldness remains less genetically complex than other complex traits. We wish to thank Yap et al. for bringing this to our attention.

AB - We have been alerted that in our recent Article the calculations used to transform the heritability from the observed scale to the liability scale did not take into account the individuals in category 2 of the baldness scale, who were removed in our original analysis. This led to an overestimation of the heritability on the liability scale, which should have been 0.62 instead of 0.94. Moreover, in the Title and in the Abstract, we report that we can explain 38% of the risk, while in fact that is the proportion of heritability explained by the loci we discovered. These errors do not substantially change the paper or its conclusions apart from the statement MBP is therefore probably one of the most heritable complex traits. Genome-wide significant associations and pathway analyses are not affected in any way and male-pattern baldness remains less genetically complex than other complex traits. We wish to thank Yap et al. for bringing this to our attention.

KW - Published Erratum

U2 - 10.1038/s41467-018-04857-7

DO - 10.1038/s41467-018-04857-7

M3 - Article

C2 - 29959320

SN - 2041-1723

VL - 9

SP - 2536

JO - Nature Communications

JF - Nature Communications

IS - 1

ER -

Author Correction: GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk

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GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk

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