Baseline MRI delivery characteristics predict change in invasive ductal breast carcinoma PET metabolism as a result of primary chemotherapy administration

S I K Semple, R T Staff, S D Heys, T W Redpath, A E Welch, T S Ahearn, Aw Hutcheon, F J Gilbert

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of the study was to investigate whether pre-therapy vascular delivery assessment [using dynamic contrast enhanced magnetic resonance imaging (DCE-MRI)] can predict reduction in breast cancer metabolism [detected using 2-[(18)F] fluoro-2-deoxy-D-glucose positron emission tomography ((18)F(-)FDG-PET)] after a single cycle of chemotherapy. Reduction in (18)F-FDG PET metabolism has previously been shown to correlate with histological response to primary chemotherapy.
Original languageEnglish
Pages (from-to)1393-8
Number of pages6
JournalAnnals of Oncology
Volume17
Issue number9
DOIs
Publication statusPublished - 2006

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