Benign vaginal polyp: a histological, histochemical and immunohistochemical study of 20 polyps with comparison to normal vaginal subepithelial layer

A I al-Nafussi, G Rebello, D Hughes, K Blessing

Research output: Contribution to journalArticlepeer-review

Abstract

Twenty benign vaginal polyps from 18 patients, together with sections from normal vaginal epithelium, were studied histologically, histochemically using elastic van Gieson stain and immunohistochemically using monoclonal antibodies against vimentin, desmin and actin. The striking finding was the similarity, both histologically and immunohistochemically, of the stroma of vaginal polyps to that of the loose subepithelial layer found in normal vagina. The important difference was the marked degeneration of the elastic tissue, increased number of stellate and giant fibroblasts and subepithelial condensation of fibroblasts in the polyps. These findings support the hypothesis that vaginal polyps may represent a reactive hyperplasia of the loose subepithelial zone of the vaginal wall.

Original languageEnglish
Pages (from-to)145-50
Number of pages6
JournalHistopathology
Volume20
Issue number2
Publication statusPublished - Feb 1992

Keywords

  • Adult
  • Aged
  • Epithelial Cells
  • Female
  • Histocytochemistry
  • Humans
  • Immunoenzyme Techniques
  • Middle Aged
  • Polyps
  • Vagina
  • Vaginal Neoplasms

Fingerprint Dive into the research topics of 'Benign vaginal polyp: a histological, histochemical and immunohistochemical study of 20 polyps with comparison to normal vaginal subepithelial layer'. Together they form a unique fingerprint.

Cite this