Binding of serotonin to the human serotonin transporter. Molecular modeling and experimental validation

Engineering & Materials Science

• Molecular modeling 100%
• Ligands 87%
• Amines 39%
• Mutagenesis 26%
• Molecular structure 21%
• Crystal structure 21%
• Salts 15%
• Proteins 15%

Chemical Compounds

• Serotonin 73%
• Molecular Modeling 59%
• Primary Amine 21%
• Indole 20%
• Kd 16%
• Neurotransmitter 12%
• Leucine 11%
• Site-Directed Mutagenesis 11%
• Structure-Activity Relationship 9%
• Crystal Structure 5%
• Ligand 4%

Medicine & Life Sciences

• Serotonin Plasma Membrane Transport Proteins 82%
• Serotonin 56%
• Ligands 14%
• indole 13%
• Hydroxyl Radical 11%
• Amines 10%
• Bacterial Structures 7%
• Sequence Alignment 6%
• Molecular Structure 6%
• Structure-Activity Relationship 5%
• Site-Directed Mutagenesis 5%
• Leucine 5%
• Salts 4%
• Neurotransmitter Agents 4%
• Proteins 1%