Biosensors in bioprocess monitoring and control: current trends and future prospects

Chris French, Chris Gwenin

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The application of sensors to bioprocess monitoring of fermentation parameters such as pH, temperature, and dissolved oxygen, once a major challenge, is now a standard procedure irrespective of the scale of fermentation because the enabling technologies are well established. Offline monitoring of other parameters, such as substrate utilization and product formation, is also important but this involves inevitable delays, with implications for process control and management. In this chapter, we examine the scientific basis underlying biosensor design and control and explore the potential benefits of their applications.
Original languageEnglish
Title of host publicationFermentation Microbiology and Biotechnology
EditorsMansi El-Mansi, Charlie Bryce, Arnold Demain, Tony Allman, Sergio Sanchez, Boutaib Dahhou
Place of PublicationBoca Raton, FL
PublisherCRC PRESS-TAYLOR & FRANCIS GROUP
Pages369-402
Number of pages34
Edition3
ISBN (Print)978-1-4398-5579-9
Publication statusPublished - 2012

Keywords

  • biosensors, bioprocessing, fermentation, bioreactors

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