The application of sensors to bioprocess monitoring of fermentation parameters such as pH, temperature, and dissolved oxygen, once a major challenge, is now a standard procedure irrespective of the scale of fermentation because the enabling technologies are well established. Offline monitoring of other parameters, such as substrate utilization and product formation, is also important but this involves inevitable delays, with implications for process control and management. In this chapter, we examine the scientific basis underlying biosensor design and control and explore the potential benefits of their applications.
|Title of host publication||Fermentation Microbiology and Biotechnology|
|Editors||Mansi El-Mansi, Charlie Bryce, Arnold Demain, Tony Allman, Sergio Sanchez, Boutaib Dahhou|
|Place of Publication||Boca Raton, FL|
|Publisher||CRC PRESS-TAYLOR & FRANCIS GROUP|
|Number of pages||34|
|Publication status||Published - 2012|
- biosensors, bioprocessing, fermentation, bioreactors