Bleeding in acute coronary syndromes and percutaneous coronary interventions: position paper by the Working Group on Thrombosis of the European Society of Cardiology

Philippe Gabriel Steg, Kurt Huber, Felicita Andreotti, Harald Arnesen, Dan Atar, Lina Badimon, Jean-Pierre Bassand, Raffaele De Caterina, John A Eikelboom, Dietrich Gulba, Martial Hamon, Gérard Helft, Keith A A Fox, Steen D Kristensen, Sunil V Rao, Freek W A Verheugt, Petr Widimsky, Uwe Zeymer, Jean-Philippe Collet

Research output: Contribution to journalArticlepeer-review

Abstract

Bleeding has recently emerged as an important outcome in the management of acute coronary syndromes (ACS), which is relatively frequent compared with ischaemic outcomes and has important implications in terms of prognosis, outcomes, and costs. In particular, there is evidence that patients experiencing major bleeding in the acute phase are at higher risk for death in the following months, although the causal nature of this relation is still debated. This position paper aims to summarize current knowledge regarding the epidemiology of bleeding in ACS and percutaneous coronary intervention, including measurement and definitions of bleeding, with emphasis on the recent consensus Bleeding Academic Research Consortium (BARC) definitions. It also provides an European perspective on management strategies to minimize the rate, extent, and consequences of bleeding. Finally, the research implications of bleeding (measuring and reporting bleeding in trials, the importance of bleeding as an outcome measure, and bleeding as a subject for future research) are also discussed.
Original languageEnglish
Pages (from-to)1854-64
Number of pages11
JournalEuropean Heart Journal
Volume32
Issue number15
DOIs
Publication statusPublished - 2011

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