BMI is superior to symptoms in predicting response to proton pump inhibitor: randomised trial in patients with upper gastrointestinal symptoms and normal endoscopy

Jonathan Fletcher; Mohammad H Derakhshan; Gareth Jones; Angela A Wirz; Kenneth E L McColl

doi:10.1136/gut.2010.228064

BMI is superior to symptoms in predicting response to proton pump inhibitor: randomised trial in patients with upper gastrointestinal symptoms and normal endoscopy

Jonathan Fletcher, Mohammad H Derakhshan, Gareth Jones, Angela A Wirz, Kenneth E L McColl

Research output: Contribution to journal › Article › peer-review

Abstract

In most patients undergoing endoscopy for upper gastrointestinal (GI) symptoms in the Western world, no macroscopic abnormality or evidence of Helicobacter pylori infection is identified. Following this negative investigation, proton pump inhibitor (PPI) therapy is usually prescribed. The aim of this study was to assess the value of such treatment compared with placebo and to identify predictors of response.

Original language	English
Pages (from-to)	442-8
Number of pages	7
Journal	Gut
Volume	60
Issue number	4
DOIs	https://doi.org/10.1136/gut.2010.228064
Publication status	Published - 2011

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10.1136/gut.2010.228064

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title = "BMI is superior to symptoms in predicting response to proton pump inhibitor: randomised trial in patients with upper gastrointestinal symptoms and normal endoscopy",

abstract = "In most patients undergoing endoscopy for upper gastrointestinal (GI) symptoms in the Western world, no macroscopic abnormality or evidence of Helicobacter pylori infection is identified. Following this negative investigation, proton pump inhibitor (PPI) therapy is usually prescribed. The aim of this study was to assess the value of such treatment compared with placebo and to identify predictors of response.",

author = "Jonathan Fletcher and Derakhshan, {Mohammad H} and Gareth Jones and Wirz, {Angela A} and McColl, {Kenneth E L}",

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AU - Wirz, Angela A

AU - McColl, Kenneth E L

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AB - In most patients undergoing endoscopy for upper gastrointestinal (GI) symptoms in the Western world, no macroscopic abnormality or evidence of Helicobacter pylori infection is identified. Following this negative investigation, proton pump inhibitor (PPI) therapy is usually prescribed. The aim of this study was to assess the value of such treatment compared with placebo and to identify predictors of response.

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DO - 10.1136/gut.2010.228064

M3 - Article

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SP - 442

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JO - Gut

JF - Gut

IS - 4

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BMI is superior to symptoms in predicting response to proton pump inhibitor: randomised trial in patients with upper gastrointestinal symptoms and normal endoscopy

Abstract

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