BODIPY-Labeled Cyclobutanes by Secondary C(sp3)─H Arylations for Live-Cell Imaging

Matteo Virelli, Wei Wang, Rositha Kuniyil, Jun Wu, Giuseppe Zanoni, Antonio Fernandez Vargas, Jamie Scott, Marc Vendrell Escobar, Lutz Ackermann

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Arylated cyclobutanes were accessed by a versatile palladium-catalyzed secondary C(sp3)–H activations exploiting chelation assistance by modular triazoles. The C−H arylation led to cyclobutane natural product derivatives in a highly regioselective fashion, setting the stage for the rapid access to novel fluorogenic BODIPY-labeled probes for live-cell imaging.

Original languageEnglish
JournalChemistry - A European Journal
Early online date21 Aug 2019
DOIs
Publication statusPublished - Oct 2019

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