Abstract / Description of output
Brønsted acid‐catalyzed general Petasis allylation and isoprenylation of unactivated ketones have been developed using o ‐hydroxyaniline and the corresponding pinacolyl boronic esters. This robust methodology has provided access to a broad variety of quaternary homoallylic amines and dienylamines in high yields, proved applicable to a gram‐scale synthesis, and allowed the formation of a potentially bioactive quaternary homoallylic aminodiol.
Original language | English |
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Journal | Chemistry - A European Journal |
Early online date | 20 May 2020 |
DOIs | |
Publication status | E-pub ahead of print - 20 May 2020 |