Broad consent for future research: International perspectives

Mark A. Rothstein, Heather L. Harrell, Katie M. Saulnier, Edward S. Dove, Chien Te Fan, Tzu-Hsun Hung , Obiajulu Nnamuchi, Alexandra Obadia, Gil Siegal, Bartha Maria Knoppers

Research output: Contribution to journalLetterpeer-review

Abstract

In the United States, final amendments to the Federal Policy for the Protection of Human Subjects (“the Common Rule”) were published on January 19, 2017, and they will take effect on January 21, 2019. One of the most widely discussed provisions is that for the first time, federal regulations governing research with humans authorize the use of broad consent for future, unspecified research on individually identifiable biospecimens and associated data. Many questions have been raised about broad consent, including what effect it will have on research and whether it adequately protects the interests of research participants.

There are lessons to be learned for the U.S. and other countries by looking to countries that already have experience with broad consent for biobank collection and with the storage and subsequent use of the biospecimens and data. This article describes how broad consent works in five countries—Canada (in Quebec), Israel, Nigeria, Taiwan, and the United Kingdom—and with different types of biobanks: national biobanks, federated biobanks, and regional biobanks. Evaluating the provisions and challenges of the broad consent approaches in these countries can inform policies for this increasingly used approach to biobank regulation.
Original languageEnglish
Pages (from-to)7-12
Number of pages6
JournalEthics & Human Research
Volume40
Issue number6
DOIs
Publication statusPublished - 1 Nov 2018

Keywords

  • human subjects research
  • biobanks
  • biospecimen research
  • broad consent
  • Common Rule

Fingerprint

Dive into the research topics of 'Broad consent for future research: International perspectives'. Together they form a unique fingerprint.

Cite this