Building consensus in neuromesodermal research: Current advances and future biomedical perspectives

Anahí Binagui-Casas, André Dias*, Charlène Guillot, Vicki Metzis, Dillan Saunders

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract / Description of output

The development of the vertebrate body axis relies on the activity of different populations of axial progenitors, including neuromesodermal progenitors. Currently, the term ‘Neuromesodermal progenitors’ is associated with various definitions. Here, we use distinct terminologies to highlight advances in our understanding of this cell type at both the single-cell and population levels. We discuss how these recent insights prompt new opportunities to address a range of biomedical questions spanning cancer metastasis, congenital disorders, cellular metabolism, regenerative medicine, and evolution. Finally, we outline some of the major unanswered questions and propose future directions at the forefront of neuromesodermal research.
Original languageEnglish
Pages (from-to)133-140
Number of pages8
JournalCurrent opinion in cell biology
Volume73
Early online date28 Oct 2021
DOIs
Publication statusE-pub ahead of print - 28 Oct 2021

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