TY - JOUR
T1 - Burden of neglected tropical diseases and access to medicine and diagnostics in Ethiopia
T2 - a scoping review
AU - Semahegn, Agumasie
AU - Manyazewal, Tsegahun
AU - Getachew, Eyerusalem
AU - Fekadu, Bethelhem
AU - Assefa, Esubalew
AU - Kassa, Munir
AU - Davey, Gail
AU - Hopkins, Michael
AU - Araya, Mesele
AU - Woldehanna, Tassew
AU - Hanlon, Charlotte
AU - Fekadu, Abebaw
N1 - Funding Information: This work was supported by the Wellcome Trust (Grant ID 221576/Z/20/Z). We would also like to thank the CDT-Africa, Addis Ababa University, University of Sussex and National Institute of Health Research (NIHR)-Wellcome Global Health Research Partnership, UK, for the financial support. AF receives support from the NIHR-Wellcome Trust to the Unit for Health Evidence and Policy (UHEP) Ethiopia (Grant ID 221576/Z/20/Z), and NIHR Global Health Research Unit on Neglected Tropical Diseases-Phase 1 (G2153) & Phase 2 (G3417). CH receives support from the National Institute of Health and Care Research through the NIHR Global Health Research Group on Homelessness and Mental Health in Africa (NIHR134325) and the SPARK project (NIHR200842) using UK aid from the UK Government. The views expressed in this publication are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care. CH receives support from the Wellcome Trust through grants 222154/Z20/Z and 223615/Z/21/Z. Funding Information: This work was supported by the Wellcome Trust (Grant ID 221576/Z/20/Z). We would also like to thank the CDT-Africa, Addis Ababa University, University of Sussex and National Institute of Health Research (NIHR)-Wellcome Global Health Research Partnership, UK, for the financial support. AF receives support from the NIHR-Wellcome Trust to the Unit for Health Evidence and Policy (UHEP) Ethiopia (Grant ID 221576/Z/20/Z), and NIHR Global Health Research Unit on Neglected Tropical Diseases-Phase 1 (G2153) & Phase 2 (G3417). CH receives support from the National Institute of Health and Care Research through the NIHR Global Health Research Group on Homelessness and Mental Health in Africa (NIHR134325) and the SPARK project (NIHR200842) using UK aid from the UK Government. The views expressed in this publication are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care. CH receives support from the Wellcome Trust through grants 222154/Z20/Z and 223615/Z/21/Z. Funding Information: This work was financially supported by Wellcome Trust, UK (Grant ID 221576/Z/20/Z). The funder has no role on the technical work and interpretation of the finding which is the responsibility of authors. Publisher Copyright: © 2023, BioMed Central Ltd., part of Springer Nature.
M1 - 140
PY - 2023/8/14
Y1 - 2023/8/14
N2 - BACKGROUND: More than 1.7 billion people are affected by neglected tropical diseases (NTDs) worldwide. Forty percent of the NTD-affected people live in Africa with the poorest, most vulnerable, and hard to reach geographical areas. The NTDs cause significant social and economic burden and deepen marginalization and stigmatization. The World Health Organization's current roadmap for NTD aims to prevent, control, eliminate, or eradicate 20 tropical diseases. Ethiopia experiences a high burden of these diseases, but current access to diagnostics, medicine, and/or care has been little explored to inform the country's NTD strategic plan. The overall purpose of the scoping review was to map and characterize the burden of NTDs and challenges in access to diagnostics, medicine, and/or care in Ethiopia.METHODS: A systematic search of evidence was conducted in PubMed, Cochrane Library, and Google Scholar from January 2000 until May 2022, without restrictions of language or study design. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Review was followed for screening of studies. Key findings were extracted and narrated qualitatively.RESULTS: The search resulted in 4532 articles, of which 105 met the inclusion criteria and were included in the scoping review under three themes: burden of NTDs, access to diagnostics, medicine and/or care, and key barriers. Although gains have been made in the prevention and control of NTDs in Ethiopia, the burden remains high, and progress in access to diagnostics, medicine/drugs, and/or care is very slow. Poverty, poor quality of life, and underfunding of NTD programs decelerate the process of NTD elimination program in the country.CONCLUSIONS: The scoping review identified a considerable number of studies on the burden of NTDs in Ethiopia and strategies for diagnosis, treatment, and/or care; however, there is a paucity of evidence on the suitability and potential benefits of novel diagnostic technologies and medicines in the country. A regular review and analysis of such country-level evidence is important to inform the country NTDs roadmap and local implementation strategies.
AB - BACKGROUND: More than 1.7 billion people are affected by neglected tropical diseases (NTDs) worldwide. Forty percent of the NTD-affected people live in Africa with the poorest, most vulnerable, and hard to reach geographical areas. The NTDs cause significant social and economic burden and deepen marginalization and stigmatization. The World Health Organization's current roadmap for NTD aims to prevent, control, eliminate, or eradicate 20 tropical diseases. Ethiopia experiences a high burden of these diseases, but current access to diagnostics, medicine, and/or care has been little explored to inform the country's NTD strategic plan. The overall purpose of the scoping review was to map and characterize the burden of NTDs and challenges in access to diagnostics, medicine, and/or care in Ethiopia.METHODS: A systematic search of evidence was conducted in PubMed, Cochrane Library, and Google Scholar from January 2000 until May 2022, without restrictions of language or study design. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Review was followed for screening of studies. Key findings were extracted and narrated qualitatively.RESULTS: The search resulted in 4532 articles, of which 105 met the inclusion criteria and were included in the scoping review under three themes: burden of NTDs, access to diagnostics, medicine and/or care, and key barriers. Although gains have been made in the prevention and control of NTDs in Ethiopia, the burden remains high, and progress in access to diagnostics, medicine/drugs, and/or care is very slow. Poverty, poor quality of life, and underfunding of NTD programs decelerate the process of NTD elimination program in the country.CONCLUSIONS: The scoping review identified a considerable number of studies on the burden of NTDs in Ethiopia and strategies for diagnosis, treatment, and/or care; however, there is a paucity of evidence on the suitability and potential benefits of novel diagnostic technologies and medicines in the country. A regular review and analysis of such country-level evidence is important to inform the country NTDs roadmap and local implementation strategies.
KW - Humans
KW - Ethiopia/epidemiology
KW - Quality of Life
KW - Tropical Medicine/methods
KW - Global Health
KW - Neglected Diseases/diagnosis
KW - Health Services Accessibility
U2 - 10.1186/s13643-023-02302-5
DO - 10.1186/s13643-023-02302-5
M3 - Article
SN - 2046-4053
VL - 12
JO - Systematic Reviews
JF - Systematic Reviews
IS - 1
ER -