C-reactive protein, APOE genotype and longitudinal cognitive change in an older population

on behalf of the Medical Research Council Cognitive Function and Ageing Study, Thomas A S Lima, Amanda L Adler, Thais Minett, Fiona E Matthews, Carol Brayne, Riccardo E Marioni

Research output: Contribution to journalArticlepeer-review

Abstract

circulating measures of inflammatory markers, such as C-reactive protein (CRP) have been associated with an increased risk of future cognitive decline. However, the nature of the relationship among the very old (>75 years) is unclear. Cross-sectional evidence suggests that elevated CRP may even be protective in this age group. This study examines these associations longitudinally.
Original languageEnglish
JournalAge and Ageing
Volume43
Issue number2
Early online date3 Dec 2013
DOIs
Publication statusPublished - Mar 2014

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